Mark, I've had a 15 minute play one on of your pages: Marky.xar.
I suppose the main trick was to first group the images and other detail.

I just set the layout to Justify Centre & Top and added padding to come close to your page.

I did not include any HighSlideJS pop-ups as I don't like them and once you do, as you found out, you're stuck with them in the Variant.
I would use CSS to either hover a larger view or build up a number of pop-up layers, where you have total layout control.

I hope you have viewed https://www.youtube.com/playlist?lis...ykyW5rWlxeoLcf. It helps you over some of the initial hurdles.

Acorn