Xara has no problems with whole pixel integers.
For your wallpaper creation graphic I suggest:-
* Make sure all units are set to 'pixels' (no cm/in ect)
* set grid ruler spacing to decimal units (eg; 10px / 10 or 50px / 50)
* set 'snap to grid*
* Choose a New Blank Photo template
* Size your image to 1280x800
* Export (I chose JPG 20% compression)
Will be perfect
Sample using above method: http://i.imgur.com/KukRp.jpg
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