Hithere... there really and truly is no one approach to designing a website, nor one app alone with which to create such with...

Many use DreamWeaver as a web editor, in conjuction with using say PhotoShop for image editing and web element creation, to give you but one example (perhaps the most common) , myself, I personaly prefer to use PhotoImpact for web layout conception, then take the main image slices and insert them into to simple nested tables and cells built in FrontPage... using cell padding/spacing along with background coloring options found in the web editor to make up as much of the page as possible...as in apposed to having to use image spacers and the like... this is but one of many different methods one may use in designing even the simplest of sites...

...if you have an idea on what your site is going to be about, and/or can supply some graphics here to play with perhaps someone might do up an example or two in layout and code source to get you started on your way http://www.talkgraphics.com/images/smilies/biggrin.gif

till then,
happy creat'n all