Nance

Colors do change in CMYK mode as you have noticed. Bright greens and cyans become muted, purples become blue or reddish and loose a lot of their intensity.

So for CMYK output you are better off creating your colors in Simulate Print Colors.

The other factor is how accurate your display is. If your display is not well calibrated, the printed color can look markedly different. I am lucky to have a pretty reliable DELL flat panel monitor and Windows XP. So my screen color using the DELL profile is pretty accurate. My monitor is a touch warm (towards red-orange) but not enough to make a big difference. But I can predict when I print in CMYK that my colors will be a bit cooler.

Gary