I have windows 7 beta and the first application I tried was Xara Xtreme Pro 4.0 plus the patch - at first it didn't want to install saying it was an unrecognized OS version, but right clicking on the setup file on the CD and choosing compatibility for Vista, it went in no problem. Haven't had time to play (did it late last night), but it did start up with no issues. I'll send a screen shot later when I get back home.
So far this new OS looks promising.