Quote Originally Posted by gwpriester View Post
Can you isolate the layer and/or lock the other layers, and Select All and then apply your transparency?
It would be a ton of work to do that while drawing. An example of the effect I would like to achieve with the blending mode on the layer can be found at the link that I've posted in response of Acorn question.

Here is the link of the video that illustrates that: https://www.twitch.tv/videos/982294549
You should look at this time in the video 02:12:47