that is not mouse lineart surely; if it is someone had a lot of time to spare..

if I were doing it with a wacom I would do it in a raster program such as painter or sai or manga studio and then vector it afterwards with vector magic, totalvectorize or inkscape if necessary

you can probably do the first in xara given practice using the freehand tool and the wacom, but the second one looks like a caligraphy pen and xara does not have one [although you might be able to fudge it with the shapebuilder tool - but that tool being screen pixels only does not make for a pleasant workflow in this regard]