So are these sprites where the coordinates are important?

Most clients aren't too picky. Occasionally a client gets huffy if a PSD design isn't reproduced pixel-perfect.

In this case, you are only seeing the background of a panel, not anything else - there's a ton of other stuff that sits over that. This is a Flash project and unlike the static PSD, these panels are sometimes hidden then revealed, so it's often better to handle them as separate entities in Flash, so I want to position that panel in the same place as on the PSD and of the same size.

It sounds trivial, and mostly it is, but sometimes it's not!

In this case the flash panel sits over HTML elements that are also visible through flash and as a result this panel needs to sit as closely over the panel it obscures in the underlying HTML.

It will never be perfect on all browsers or any browser at all times. It wasn't my idea..