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Thank you.

It definitely should not be so slow.

A quick(ish) experiment.
Clone your design file so you keep your original safe and complete.

In the copy, delete half the pages.
Any speed...

That is not relevant as to how the pages are connected.

Are they all separate pages with their own <filename>.htm presence (Supersite) or are they wrapped up into one larger generated file,...

Still begs the question: Is the website a Supersite?
At 100+ pages a Conventional Website will not be draggy as each change is to a separate design page.

Acorn

Egg, we still need to know its construction and purpose.

Acorn

What I was trying to establish was that your site had lots of flow between pages like a document or are the web pages effectively standalone?

Acorn

So I created a text document of 160 flowed pages and 160,000 words. It is only 400kB.

A Search and Replace of 2,000 words took 30 seconds.

The delay in adding new letters for the cursor to...

I would run both as Administrator to force the applications to register their assets correctly and recheck your speed again.

Acorn