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That's right. Create your design in WebDesigner and place the php include into the placeholder. Then export the page with php extension. That's it.
Doesn't it work?
In this case you'll be able to...

Include works in PHP files.
What stops you from using PHP files?

Not iframes, of course. But there's no need to use iframe in this case. Or am I missing something?

But it can! Using the dynamic page tweak.
It's exactly the case this tweak was created for.