When I create a design project, no one has ever asked what software I use. They either like the result or they don't.

But to Paul's excellent point, unless you plan to work alone (as I have in the later stages of my career), you will need to be fluent in Adobe products. The industry is not as enlightened when it comes to this. But what it all comes down to is design software is a tool, it does not create, it just facilitates the user's vision.